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Purification

EMP Biotech, Purification, size exclusion chromatography

New Frontiers in Plasma Fractionation: IEC and SEC

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Plasma contains over 120 different proteins that help with everything from blood clotting to immunity, making it the largest and most diverse set of proteins in the human body [1]. Several of these, when purified and concentrated, become life-saving therapeutics. These plasma-derived medicinal products (PDMPs) are critical to the treatment of many diseases, including bleeding … Read more

EMP Biotech, Purification

Optimizing Use of Your Desalting Column

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How Desalting Columns Work Desalting columns use size exclusion chromatography (SEC). They may also be called gel filtration columns, size-exclusion columns, or buffer exchange columns. The resin inside contains porous beads, typically made of cross-linked dextran (e.g. Zetadex, or Sephadex). Large molecules like proteins or nucleic acids cannot enter the bead pores and elute quickly, … Read more

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