ADTT – 5-Amino-3H-1,2,4-dithiazole-3-thione (Xanthane Hydride) is a high-purity sulfurizing reagent used during oligonucleotide synthesis. It facilitates the incorporation of sulfur into the phosphorothioate backbone, a modification that enhances nuclease resistance and improves the stability of synthetic DNA and RNA oligos.

This reagent is ideal for labs requiring reliable sulfurization chemistry for therapeutic oligonucleotide development, gene silencing applications, or other research involving phosphorothioate oligonucleotides.

Key Features:

• Reagent type: Sulfurizing agent

• Application: Oligonucleotide synthesis (phosphorothioate linkage formation)

• Synonyms: Xanthane Hydride, ADTT

• High chemical stability and solubility in synthesis-compatible solvents

• Suitable for use in automated synthesizers

Available Sizes:

• 100g, 500g or bulk (please ask for options)

Shipping & Storage:

• Shipped at ambient temperature

• Store under dry, inert conditions

For technical details, safety documentation, or pricing on bulk quantities, please contact us.