AMA deprotection reagent (50:50 v/v ammonia 40% and aqueous methylamine) offers rapid and efficient cleavage and base deprotection of oligonucleotides in standard synthesis workflows.
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AMA – Concentrated Ammonia : Aqueous Methylamine (50:50 v/v)
This reagent is a 50:50 mixture of 40% concentrated ammonium hydroxide and aqueous methylamine, designed for rapid cleavage and base deprotection of oligonucleotides synthesized on solid-phase supports.
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Composition: 50:50 (v/v) concentrated ammonia (40%) and aqueous methylamine
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Application: Oligonucleotide cleavage and base deprotection
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Compatibility: Standard and high-throughput oligo synthesis
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Format: Ready-to-use
AMA is one of the most widely used deprotection solutions in modern oligonucleotide synthesis due to its short reaction times and compatibility with a variety of protecting group strategies.
