Capping B1 solution with 40% acetic anhydride in acetonitrile, optimized for ÄKTA Oligopilot systems, supports efficient 5’-OH protection in oligonucleotide synthesis workflows.
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Capping B1 – 40% Acetic Anhydride in Acetonitrile (for ÄKTA Oligopilot)
This Capping Reagent B1 is a ready-to-use solution of 40% acetic anhydride in acetonitrile, specifically formulated for use in ÄKTA Oligopilot synthesizers during the capping step of solid-phase oligonucleotide synthesis.
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Composition: 40% acetic anhydride in acetonitrile (v/v)
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Function: Reagent for 5’-OH capping
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Application: Used with ÄKTA Oligopilot instruments
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Formulation: Ready-to-use, high-purity standard
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Packaging: Amber glass bottle with inert gas overlay
Capping B1 serves as the acetylating agent in combination with an activator (Capping Reagent A), ensuring the removal of failure sequences by protecting unreacted 5′-hydroxyl groups. Its elevated concentration is tailored to meet the performance needs of large-scale or process-driven synthesis.
