Phenylacetyl Disulfide (PADS) Pads – Solid Sulfurizing Reagent

Phenylacetyl disulfide (PADS) is a widely used sulfurizing reagent for the introduction of phosphorothioate linkages in oligonucleotide synthesis. Solid PADS reagents offer a convenient and easy-to-handle alternative to traditional liquid reagents, simplifying synthesis workflows and reducing exposure to reactive chemicals.

The PADS reagent efficiently replaces non-bridging oxygen atoms with sulfur, producing phosphorothioate oligos that exhibit improved resistance to nuclease degradation—making them suitable for therapeutic, diagnostic, and research use.

Key Features:

• Reagent: Phenylacetyl Disulfide (PADS)

• Form: Solid

• Application: Sulfurization of phosphorothioate oligonucleotides

• High-purity for synthesis-grade use

• Convenient and clean handling, ideal for automation

• Compatible with standard oligo synthesizers

Handling & Storage:

• Store under dry, inert conditions

• Ready to use out of the package

Available Formats:

• 5g, 25g and 500 g

For ordering information or larger-scale custom packaging, please contact us.