Fluorescent Dye Label Options: DiR, DiD, DiI, DiO, None
Surface Coating Options: Carboxyl, Methoxy PEG, Azide PEG
Amount Options: 10 mg, 50 mg

Description
Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Dye molecules and magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry)

Features
Made with FDA approved biocompatible and biodegradable PLGA polymer.
Conjugation-ready for covalent attachment of biomolecules.
High degree of monodispersity.
Can be pulled down by application of magnetic force.
Labeled with a fluorescent dye.
(Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
(Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

Applications
Dual labeled fluorescence and magnetic nanoparticles for in-vivo tar-geting.
Dual fluorescence and MRI imaging for in vitro and in vivo applications.
Dual labeled fluorescence and magnetic probes for magnetic cell pull-down and flowcytometry analysis.
In vitro and in vivo delivery of proteins and small molecules.

Product is supplied as lyophilized powder.