Surface Coating: Methoxy PEG
Amount: 50 mg

Description

Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry)

Features
Made with FDA approved biocompatible and biodegradable PLGA polymer.
Conjugation-ready for covalent attachment of biomolecules.
High degree of monodispersity.
Can be pulled down by application of magnetic force.
(Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
(Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

Applications
Magnetic nanoparticles for in-vivo targeting.
Probes for MRI imaging for in vitro and in vivo applications.
Magnetic probes for magnetic cell and small molecule pulldown.
In vitro and in vivo delivery of proteins and small molecules.

Product is supplied as lyophilized powder.