PuroSPIN™ Gel Extraction Kit is designed to provide simple and easy-to-use method for extraction and purification of DNA samples (100 bp − 10 kbp) from agarose and PAGE gels. The purification technology is based on dissolving the gel embedded DNA in a buffer solution, followed by nucleic acid binding to silica spin-columns, which allows efficient removal of gel residues and other contaminants. Silica spin columns offer faster, simpler and safer alternative to traditional nucleic acid purification techniques such as phenol-chloroform extraction. PuroSPIN™ buffer formulations produce highly purified DNA product for downstream applications, such as PCR, restriction digestion, ligation, labeling, or sequencing.