CentriPure 384, a 384 well Desalting Plate (Hydrated, 135 µL)

The CentriPure 384-well plate is pre-packed with hydrated Zetadex-25, emp Biotech’s proprietary gel filtration resin. It offers efficient desalting, buffer exchange, and sample cleanup of DNA, RNA, and small biomolecules in 384-well format, ideal for high-throughput environments.

Key Features:

• Fully hydrated 384 well desalting plate
• Resin: Zetadex-25
• Plate format: Standard 384-well
• Bed volume per well: 100 µL
• Working range: 8 µL per well
• MWCO: 10 nt / 10 bp

Applications:

• Desalting of oligonucleotides, DNA, RNA
• Buffer exchange for enzymatic reactions
• Dye, salt, and small molecule removal
• High-throughput purification before PCR, sequencing, or storage

Benefits:

• Fast and simple gravity-flow processing
• Minimal sample loss
• Reproducible performance across wells
• Compatible with liquid handling systems

References

• Current approaches for purification of antibody-drug conjugates. Journal of Separation Science 2021.
• In Vitro Oxidative Crosslinking of Recombinant Barnacle Cyprid Cement Gland Proteins. Marine Biotechnology 2021.
• Photoinduced Bleaching in an Efficient Singlet Oxygen Photosensitizing Protein: Identifying a Culprit in the Flavin-Binding LOV-Based Protein SOPP3. Journal of Photochemistry and Photobiology A: Chemistry 2022.
• AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production. ChemRxiv 2023.
• Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes. Nature Communications 2023.
• AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production. Bioconjugate Chemistry 2023.