Hyacinth Oxidizer – 0.05 M Iodine in Pyridine/Water (90:10 v/v) for DNA and RNA Synthesis

The Hyacinth Oxidizer is a high-concentration oxidation reagent used in the phosphoramidite method of oligonucleotide synthesis. It contains 0.05 M iodine dissolved in a 90:10 mixture of pyridine and water — a THF-free formulation that may be preferred for specific synthesis platforms or protocols.

This reagent is used in the oxidation step to convert phosphite triester linkages to stable phosphate diesters, finalizing each nucleotide addition. Its increased iodine concentration may offer faster reaction kinetics or increased efficiency under certain conditions.

Key Features:

• 0.05 M iodine in pyridine/water (90:10 v/v)

• Higher-concentration formulation than standard oxidizers

• THF-free solvent system

• High-purity, synthesis-grade reagent

• Optimized for oxidation in DNA/RNA synthesis workflows

• Supplied ready to use in sealed containers

Applications:

• Phosphoramidite oligonucleotide synthesis

• Automated or manual DNA/RNA synthesis protocols

• Labs requiring THF-free or higher-strength oxidation solutions

Distribution:

• Available in Denmark, Sweden, Norway, and Iceland

• Fast, reliable shipping and support from YouDoBio