Ultramild deprotection solution (ammonium hydroxide:ethanol, 75:25 v/v) is ideal for oligonucleotide synthesis protocols requiring gentle cleavage and base deprotection.
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Ultramild Deprotection Solution – 75:25 Ammonium Hydroxide : Ethanol
This reagent is a 75:25 (v/v) mixture of ammonium hydroxide and ethanol, specifically formulated for ultramild deprotection and cleavage of oligonucleotides from solid-phase supports.
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Composition: 75:25 ammonium hydroxide : ethanol (v/v)
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Application: Cleavage and base deprotection
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Compatibility: Ultramild oligonucleotide synthesis protocols
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Format: Ready-to-use
The solution is particularly suitable for use with ultramild protecting groups and is compatible with many sensitive oligo modifications (e.g., fluorescent dyes, base analogs).

