0.25 M solution of 4,5-dicyanoimidazole (DCI) in anhydrous acetonitrile. A trusted activator for oligonucleotide synthesis using phosphoramidite chemistry.
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Product Overview
This product is a 0.25 M solution of 4,5-dicyanoimidazole (DCI) in anhydrous acetonitrile. DCI is a well-established activator used in the phosphoramidite method for oligonucleotide synthesis.
Key Features
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Concentration: 0.25 M
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Solvent: Anhydrous acetonitrile
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High purity for reliable coupling efficiency
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Excellent reagent stability
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Suitable for automated DNA/RNA synthesis platforms
Application
DCI acts as a nucleophilic catalyst, facilitating the coupling step between nucleoside phosphoramidites and the growing oligonucleotide chain. This lower concentration (0.25 M) is ideal for systems optimized for reduced reagent volume or for extended synthesis protocols where slower activation may be beneficial.
| Packaging | 450 mL, 28-400 thread, 2.5 L GL45, thread, 4.0 L, GL45 thread, 4.0 L, US38 thread, Bulk |
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