0.02 M iodine solution in THF/pyridine/water (90.6:0.4:9 v/v/v). Used in the oxidation step of oligonucleotide synthesis. Low-pyridine, high-purity formulation.
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Iodine Oxidizer Solution – For Oligonucleotide Synthesis (0.02 M Iodine in THF/Pyridine/Water 90.6:0.4:9 v/v/v)
This iodine oxidizer is specifically formulated with 0.02 M iodine in a 90.6:0.4:9 mixture of THF, pyridine, and water. The blend is optimized for the oxidation step in phosphoramidite-based oligonucleotide synthesis, where it converts phosphite triesters into stable phosphate diesters.
The slightly adjusted THF/pyridine/water ratio may improve compatibility with certain synthesis platforms or meet specific reagent handling preferences — offering a low-pyridine profile with balanced reactivity.
This solution is supplied ready to use, with synthesis-grade quality and moisture-resistant packaging for consistent performance.
Key Features:
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Formulation: 0.02 M iodine in THF/pyridine/water (90.6:0.4:9 v/v/v)
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High-purity reagent for DNA and RNA synthesis
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Used in oxidation step of phosphoramidite workflows
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Low-pyridine formulation for select systems or protocols
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Supplied in sealed containers for stability
- Available in volumes from 450 mL to bulk
Applications:
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Oligonucleotide synthesis (oxidation step)
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Phosphite-to-phosphate conversion in DNA synthesis
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Automated and manual synthesis platforms
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Suitable for workflows requiring minimal pyridine exposure
Distribution:
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Available across Denmark, Sweden, Norway, Finland, and Iceland
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Supplied by YouDoBio with fast delivery and local support

