CentriPure 10, a 1 mL desalting column – Gravity Flow Purification for DNA, RNA, and Proteins

The CentriPure 10 Gel Filtration Column is a pre-packed gravity-flow column designed for fast and efficient desalting, buffer exchange, and removal of small molecules from biomolecules such as DNA, RNA, oligonucleotides, and proteins.

CentriPure 10 columns retain nucleic acids and proteins while removing salts, enzymes, dyes, or other low-molecular-weight contaminants.

Key Features:

• Gravity-flow gel filtration (1 mL desalting column) – no centrifugation required

• MWCO: ~10 base pairs for nucleotides and 5 kDa for globular proteins.

• Pre-packed with Zetadex-25 resin for high resolution

• Suitable for desalting and buffer exchange of DNA, RNA, and proteins

Applications:

• Desalting of oligonucleotides and nucleic acids

• Removal of unincorporated dyes or nucleotides

• Protein buffer exchange or cleanup

• Fast purification in synthesis or labeling workflows

Each column is ready to use and delivers high reproducibility, sample integrity, and low sample dilution — making it a trusted solution for molecular biology and bioanalytical applications.

Interested in testing CentriPure P10 columns?

References

• Tuning the PEG surface density of the PEG-PGA enveloped Octaarginine-peptide Nanocomplexes. Drug Delivery and Translational Research 2019
• Quantifying Heme-Protein Maturation from Ratiometric Fluorescence Lifetime Measurements on the Single Fluorophore in Its GFP Fusion. The Journal of Physical Chemistry A 2020.
• Chitinases of wheat seedling and their biochemical properties. AJAB 2020.
• Chemical zymogens for the protein cysteinome. Nature Communications 2022.
• Sandwich immunoassay for adrenomedullin precursor and its practical application. Nature Scientific Reports 2024.